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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKA
All Species:
10.61
Human Site:
S98
Identified Species:
15.56
UniProt:
O14965
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14965
NP_003591.2
403
45809
S98
P
L
N
N
T
Q
K
S
K
Q
P
L
P
S
A
Chimpanzee
Pan troglodytes
XP_525364
403
45791
S98
P
L
N
N
T
Q
K
S
K
Q
P
L
P
S
A
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
S165
S
P
L
L
P
M
S
S
P
K
A
A
V
Q
L
Dog
Lupus familis
XP_853397
405
45606
S99
S
L
N
N
T
Q
K
S
E
Q
P
S
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P97477
395
44754
G98
N
E
Q
P
A
A
S
G
N
D
S
E
K
E
Q
Rat
Rattus norvegicus
P59241
397
44856
A98
S
E
Q
P
Q
P
A
A
S
G
N
N
S
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
D31
K
R
Q
W
S
L
D
D
F
D
I
G
R
P
L
Chicken
Gallus gallus
XP_425725
409
46456
N102
G
P
Q
V
P
S
K
N
S
E
K
P
Q
Q
A
Frog
Xenopus laevis
Q91819
408
46443
P100
G
P
N
E
N
R
N
P
Q
Q
T
S
H
S
S
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
L48
V
K
S
N
S
K
V
L
S
I
D
D
F
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
G56
S
P
R
D
F
E
M
G
A
H
L
G
R
G
K
Honey Bee
Apis mellifera
XP_395732
327
37711
T55
I
T
N
N
K
K
Q
T
D
K
K
W
V
L
T
Nematode Worm
Caenorhab. elegans
O01427
305
34731
G33
T
I
N
D
F
E
I
G
R
P
L
G
K
G
K
Sea Urchin
Strong. purpuratus
XP_001181990
278
32048
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
A10
Y
Q
A
A
S
E
A
A
Q
K
R
W
T
T
S
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
K95
H
E
N
K
K
L
P
K
F
K
S
L
S
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
47.7
89.8
N.A.
82.6
83.6
N.A.
65.5
73.1
65.9
53.3
N.A.
38.4
53
46.6
50.6
Protein Similarity:
100
100
62.2
93
N.A.
86.8
87.3
N.A.
70.2
82.8
77.2
65.7
N.A.
57.8
67
56.3
60
P-Site Identity:
100
100
6.6
73.3
N.A.
0
0
N.A.
0
13.3
20
6.6
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
100
13.3
80
N.A.
0
6.6
N.A.
6.6
26.6
40
26.6
N.A.
13.3
40
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.3
57.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
7
7
13
13
7
0
7
7
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
7
7
7
13
7
7
0
7
7
% D
% Glu:
0
19
0
7
0
19
0
0
7
7
0
7
0
13
0
% E
% Phe:
0
0
0
0
13
0
0
0
13
0
0
0
7
0
0
% F
% Gly:
13
0
0
0
0
0
0
19
0
7
0
19
0
13
0
% G
% His:
7
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% H
% Ile:
7
7
0
0
0
0
7
0
0
7
7
0
0
0
7
% I
% Lys:
7
7
0
7
13
13
25
7
13
25
13
0
13
0
19
% K
% Leu:
0
19
7
7
0
13
0
7
0
0
13
19
0
13
13
% L
% Met:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
44
32
7
0
7
7
7
0
7
7
0
0
0
% N
% Pro:
13
25
0
13
13
7
7
7
7
7
19
7
13
7
0
% P
% Gln:
0
7
25
0
7
19
7
0
13
25
0
0
7
13
7
% Q
% Arg:
0
7
7
0
0
7
0
0
7
0
7
0
13
0
0
% R
% Ser:
25
0
7
0
19
7
13
25
19
0
13
13
19
25
13
% S
% Thr:
7
7
0
0
19
0
0
7
0
0
7
0
7
7
7
% T
% Val:
7
0
0
7
0
0
7
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
13
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _